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Amyloid precursor protein mRNA levels in the mononuclear blood cells of Alzheimer's and Down's patients

✍ Scribed by Buckland, Paul; Tidmarsh, Simon; Spurlock, Gillian; Kaiser, Fawad; Yates, Martin; O'Mahony, Gerald; McGuffin, Peter

Book ID: 123178601
Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 573 KB
Volume: 18
Category: Article
ISSN: 0169-328X
DOI: 10.1016/0169-328X(93)90095-7

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## Abstract The precise function of APP (Alzheimer's amyloid precursor protein) remains to be fully elucidated, but various lines of evidence suggest that it may be involved in cell adhesion processes. Because APP is a transmembrane glycoprotein, variations in its expression level may have direct b