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Amplification of the Y Chromosome in Three Murine Tumor Cell Lines Transformed in vivo by Different Human Prostate Cancers

✍ Scribed by Asha S. Multani, Mustafa Ozen, Alpana Agrawal, Vicki L. Hopwood, Andrew C. Von Eschenbach and Sen Pathak

Book ID: 125624689
Publisher: Society for In Vitro Biology
Year: 1999
Tongue: English
Weight: 269 KB
Volume: 35
Category: Article
ISSN: 1475-2689
DOI: 10.2307/4294929

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## Abstract The loss of the Y chromosome is a frequent numerical chromosomal abnormality observed in human prostate cancer. In cancer, loss of specific genetic material frequently accompanies simultaneous inactivation of tumor suppressor genes. It is not known whether the Y chromosome harbors such