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Amplification of the Y chromosome in three murine tumor cell lines transformedin vivoby different human prostate cancers

โœ Scribed by Asha S. Multani; Mustafa Ozen; Alpana Agrawal; Vicki L. Hopwood; Andrew C. Von Eschenbach; Sen Pathak

Book ID
107427626
Publisher
Society for In Vitro Biology
Year
1999
Tongue
English
Weight
634 KB
Volume
35
Category
Article
ISSN
1475-2689

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## Abstract The loss of the Y chromosome is a frequent numerical chromosomal abnormality observed in human prostate cancer. In cancer, loss of specific genetic material frequently accompanies simultaneous inactivation of tumor suppressor genes. It is not known whether the Y chromosome harbors such