To understand the mechanisms underlying increased expression of Myc protein in human urinary bladder cancer, expression of c-myc mRNA and the copy number of the c-myc gene were determined. Expression of mRNA was measured by quantitative RT-PCR in 40 urothelial carcinomas and in 18 histologically nor
Amplification of the EGF receptor and c-myc genes in human esophageal cancers
β Scribed by Shih-Hsin Lu; Ling-Ling Hsieh; Feng-Chi Luo; I. B. Weinstein
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- French
- Weight
- 783 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0020-7136
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Amplification of the int-2 oncogene was measured in a series of breast tumours and related to amplification of the c-myc and c-erbB-2 oncogenes, histopathological features and relapse-free and overall survival. int-2 was amplified in I I%, c-myc in 20% and c-erbB-2 in 27% of the tumours assessed. in
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