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Amplification of the c-myc oncogene in a subpopulation of human small cell lung cancer


Book ID
122461050
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
96 KB
Volume
1
Category
Article
ISSN
0169-5002

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Heterogenous amplification of myc family
โœ Masayuki Noguchi; Setsuo Hirohashi; Futoshi Hara; Akira Kojima; Yukio Shimosato; ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 687 KB

One hundred forty-two foci of small cell lung carcinoma (SCLC) from 47 patients were examined for amplification of myc family oncogenes (c-myc, N-myc, and L-myc), by dot blot hybridization using formalin-fixed and paraffin-embedded materials which were resected surgically or obtained at autopsy. Som