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Amplification of Bothc-mycandc-raf-1 Oncogenes in a Human Osteosarcoma

โœ Scribed by Ikeda, Shogo ;Sumii, Hiroshi ;Akiyama, Kosuke ;Watanabe, Sekiko ;Ito, Shiro ;Inoue, Hajime ;Takechi, Hideo ;Tanabe, Gozo ;Oda, Takuzo

Book ID
108578880
Publisher
Wiley (Blackwell Publishing)
Year
1989
Tongue
English
Weight
219 KB
Volume
80
Category
Article
ISSN
0910-5050

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Amplifications of DNA primase 1 (PRIM1)
Amplifications of DNA primase 1 (PRIM1) in human osteosarcoma
โœ Wagner V. Yotov; Hugo Hamel; George-Etienne Rivard; Martin A. Champagne; Pierre ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 133 KB

We studied the involvement of PRIM1 in osteosarcoma by differential display, Northern and Southern hybridization, as well as fluorescence in situ hybridization (FISH) on interphase nuclei. In total, 22 pediatric oncology specimens were tested. PRIM1 was found to be amplified in 41% of the samples. P