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Amplification of a circular segment of SV40 DNA

✍ Scribed by DAVOLI, DANA; FAREED, GEORGE C.

Book ID
109692721
Publisher
Nature Publishing Group
Year
1974
Tongue
English
Weight
317 KB
Volume
251
Category
Article
ISSN
0028-0836

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## Abstract Gene amplification contributes to carcinogenesis by enhancing proto‐oncogene activity and causing chromosomal instability. The ease of detecting amplified tumor‐virus sequences has encouraged use of this system as a surrogate for studying the molecular events involved in endogenous gene