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Amphotericin B-induced depression in the phagocytic function of the isolated rat liver and its prevention by nifedipine

✍ Scribed by Gaeta, G.B.; Ames, P.R.; Mansi, L.; Esposito, V.; Giusti, G.


Book ID
122029553
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
349 KB
Volume
10
Category
Article
ISSN
0168-8278

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The hepatic distribution, biliary excretion, and mass balance of liposomal amphotericin B (L-AmB) were investigated in recirculated isolated perfused rat liver. The results were compared with those from the conventional AmB formulation, amphotericin B deoxycholate (D-AmB). L-AmB was introduced as a