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Mitochondrial damage induced by fetal hyperphenylalaninemia in the rat brain and liver: Its prevention by melatonin, Vitamin E, and Vitamin C

✍ Scribed by Francisco Martínez-Cruz; Carmen Osuna; Juan M. Guerrero

Book ID
116767664
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
146 KB
Volume
392
Category
Article
ISSN
0304-3940

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✍ Francisco Martinez-Cruz; David Pozo; Carmen Osuna; Auxiliadora Espinar; Concepci 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 642 KB

Phenylketonuria (PKU) is an autosomal recessive disorder caused by a deficiency of the phenylalanine hydroxylation system and is characterized by a block in the conversion of phenylalanine (PHE) to tyrosine. We examined the effects of maternal hyperphenylalaninemia on the morphological and biochemic