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AMPA receptor activation reduces epileptiform activity in the rat neocortex

โœ Scribed by Jonas I. Addae; Nakisha Ali; Farid F. Youssef; Trevor W. Stone


Book ID
113502810
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
476 KB
Volume
1158
Category
Article
ISSN
0006-8993

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It has been suggested that endogenous chemical substances such as adenosine, released during a seizure attack, may act as anticonvulsants in vivo. To further investigate this putative role, we have tested adenosine and stable adenosine analogues for anticonvulsant activity in vitro against ictal-lik