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Ammonia and related amino acids in the pathogenesis of brain edema in acute ischemic liver failure in rats

✍ Scribed by Margaret Swain; Roger F. Butterworth; Andres T. Blei

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
634 KB
Volume
15
Category
Article
ISSN
0270-9139

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NOTE. Amino acids were measured in CSF samples obtained via indwelling cisterna magna catheters at coma stages of encephalopathy in 6 ALF rats treated with saline infusions versus 6 ALF rats treated with OA (330 mg/kg/h) at equivalent time points. \*Values significantly different from saline-treate

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Taurine (Tau), an amino acid that abounds in brain, has been implicated in inhibitory neuromodulation and osmoregulation, the latter function being manifested by Tau release along with osmotically obligated water in response to brain tissue edema. A previous study (Hilgier and Olson: J. Neurochem. 6

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