Aminovinyl ketones and aminovinyl esters as CCN building blocks for the synthesis of 1H-pyrrolo[3,2-e]1,2,4-triazines
✍ Scribed by Valery N Charushin; Nataliya N Mochulskaya; Anatoly A Andreiko; Vera I Filyakova; Mikhail I Kodess; Oleg N Chupakhin
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 93 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Unsubstituted-3-aryl-1,2,4-triazines were found to react with aminovinyl ketones and aminovinyl esters in acetic anhydride to form derivatives of 3a,4,7,7a-tetrahydro-1H-pyrrolo[3,2-e]1,2,4-triazines in good yields.
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## Abstract A novel synthesis of substituted pyrrolo[2,3‐__e__]indoles and thieno[2,3‐__e__]indoles is described. This new approach uses 1,3‐cyclohexanedione as the starting material. Diketone intermediates are obtained in four steps from the aforementioned ketone. Using these intermediates, the ti