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Aminovinyl ketones and aminovinyl esters as CCN building blocks for the synthesis of 1H-pyrrolo[3,2-e]1,2,4-triazines

✍ Scribed by Valery N Charushin; Nataliya N Mochulskaya; Anatoly A Andreiko; Vera I Filyakova; Mikhail I Kodess; Oleg N Chupakhin


Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
93 KB
Volume
44
Category
Article
ISSN
0040-4039

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✦ Synopsis


Unsubstituted-3-aryl-1,2,4-triazines were found to react with aminovinyl ketones and aminovinyl esters in acetic anhydride to form derivatives of 3a,4,7,7a-tetrahydro-1H-pyrrolo[3,2-e]1,2,4-triazines in good yields.


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✍ Roberto Martínez; Juan Sandoval Oloarte; Gustavo Avila 📂 Article 📅 1998 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 370 KB 👁 1 views

## Abstract A novel synthesis of substituted pyrrolo[2,3‐__e__]indoles and thieno[2,3‐__e__]indoles is described. This new approach uses 1,3‐cyclohexanedione as the starting material. Diketone intermediates are obtained in four steps from the aforementioned ketone. Using these intermediates, the ti