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Aminophosphonic Acids and Aminobis(phosphonic acids) as Potential Inhibitors of Penicillin-Binding Proteins

✍ Scribed by Joséphine Beck; Sonia Gharbi; Adriana Herteg-Fernea; Lionel Vercheval; Carine Bebrone; Patricia Lassaux; Astrid Zervosen; Jacqueline Marchand-Brynaert


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
318 KB
Volume
2009
Category
Article
ISSN
1434-193X

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Maltose and Maltotriose Derivatives as P
✍ Heinz Malik; Winfried Boos; Richard R. Schmidt 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 426 KB 👁 1 views

## Abstract Inhibition of substrate binding to maltose‐binding protein (MBP) was investigated with structurally modified maltose and maltotriose derivatives that were designed based on the X‐ray analysis of maltose and maltotriose bound to MBP. In maltose, positions 1a, 2a, 2b, 4b and 6b were modif