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Aminomethylation of some 4-thiazolidinones

✍ Scribed by Yu. V. Svetkin; S. A. Vasil'eva; V. M. Pronina


Book ID
112326947
Publisher
Springer US
Year
1974
Tongue
English
Weight
153 KB
Volume
10
Category
Article
ISSN
0009-3122

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A novel synthesis of some 2-imino-4-thia
✍ Firouz Matloubi Moghaddam; Leila Hojabri πŸ“‚ Article πŸ“… 2007 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 386 KB

An efficient and simple route is presented to the synthesis of some iminothiazolidinone derivatives. Ξ±-Chloro amide derivatives undergo coupling reaction with isothiocyanate in the presence of a mild base, followed by nucleophilic substitution of chlorine by the sulfur atom of isothiocyanate.