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Aminolysis of 2-hydroxy esters catalyzed by Candida antarctica lipase

✍ Scribed by Gerardo Valerio-Alfaro; Hugo S. García; Héctor Luna; Raymundo Cruz Almanza

Book ID
110226421
Publisher
Springer Netherlands
Year
2000
Tongue
English
Weight
37 KB
Volume
22
Category
Article
ISSN
0141-5492

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Kinetic resolution of 2-substituted 3-hydroxy esters was examined by lipase PS catalyzed transesterification using vinyl acetate as an acyl donor. Resolution of (±)-syn-and -anti-1a, -1e possessing a small methyl group at the C-3 position was accomplished enantioselectively. The outcome of the resol