## Abstract Reaction of __N__‐substituted amides of 2‐chloro‐ or 4‐chloronicotinic acid with CH‐acidic nitriles in the presence of a base provides a convenient access to amino derivatives of 1,6‐naphthyrid‐5(6__H__)‐one, compounds of type 4 and 5, or 2,7‐naphthyrid‐1(2__H__)‐one 7.
Amino Group Chemistry || SelectiveN-Derivatization of Aminoglycosidesen Route to New Antibiotics and Antivirals
✍ Scribed by Ricci, Alfredo
- Book ID
- 125432541
- Publisher
- Wiley-VCH Verlag GmbH & Co. KGaA
- Year
- 2007
- Weight
- 669 KB
- Category
- Article
- ISBN
- 3527317414
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Laboratorio de1 CNR dei composti de1 carbonio contenenti eteroatomi e loro applicazioni,Via Tolara di Sotto 89/a,I 40064 Ozzano-Emilia(Bologna),Italy. Summary:Regioselective opening of the thiirane ring occurs spontaneously with Group IV B organometallics such as Me3SnNR 2 and under the catalytic ac
Quarternary salts based upon 3-alkyl substituted 1-amino-1,2,3-triazolium cations (alkyl = methyl, ethyl, n-propyl, 2-propenyl, and n-butyl) have been synthesized and characterized by vibrational spectra, multinuclear NMR, elemental analysis, and DSC studies. Subsequent diazotization of these salts
## Abstract magnified image 3‐Amino‐3‐phenyl‐2‐phenylazoacrylonitrile **6** is obtained in good yield __via__ reaction of **5** with phenyl magnesium bromide. The compound **6** is readily converted into **4a**. The so formed alkanenitrile reacted with phenylmagnesium bromide to yield **8**. Compo