A convenient and practical multi-gram procedure for the connected via amides by peptide methods. Purification is either done by recrystallization or simple filtration through synthesis of second-(G2; 4a, 5a, 5d) and third-generation (G3; 6a) dendrons with orthogonally protected functional silica gel
Amino-Functionalized, Second-Generation Dendritic Building Blocks
✍ Scribed by Rainer Klopsch; Sabine Koch; A. Dieter Schlüter
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 289 KB
- Volume
- 1998
- Category
- Article
- ISSN
- 1434-193X
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✦ Synopsis
The multi-gram scale synthesis of first-and second-deprotection of the amines are shown to be strictly orthogonal processes which makes these dendrons valuable generation dendrons with Boc-and Cbz-protected amino groups in the periphery and methyl/ethyl esters at the focal building blocks for future constructions. points is described. Saponification of the esters and
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