Amino Acids in the Synthesis of Heterocyclic Systems a Novel Synthesis of Fused Pyridinones
✍ Scribed by Anton Copar; Branko Stanovnik; Miha Tišler
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 226 KB
- Volume
- 100
- Category
- Article
- ISSN
- 0037-9646
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✦ Synopsis
Enamines 5 , prepared from heterocycles with a methyl group at a-position in respect to ring nitrogen atom 1 and N,N-dimethylformamide dimethyl acetal
( 3 ) or t-buthoxy-bis(dimethy1amino)methane (4), are transformed with 2-phenyl-5(4H)-oxazolone (1) into the corresponding intermediates 2, which cyclize into azinopyridinones 11. The method represents a novel synthesis of this class
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