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Amino acids derivatives that stabilize secondary structures of polypeptides-- : I. Synthesis of LL-3-amino-2-piperidone-6-carboxylic acid (LL-Acp), a novel beta-turn-forming amino acid

✍ Scribed by D.S. Kemp; Eric T. Sun

Book ID: 104221141
Publisher: Elsevier Science
Year: 1982
Tongue: French
Weight: 109 KB
Volume: 23
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)87699-6

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✦ Synopsis

A six-step synthesis is reported of LL-3-amino-2-piperidone-6-carboxylic acid from C-homoserine lactone and the mono-t-butyl ester of fj-benzyloxycarbonylaminomalonic acid.

Evidence of chiral integrityziscussed.

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