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Amino acid derivatives that stabilize secondary structures of polypeptides : II. The most stable conformation of peptides containing 3-amino-2-piperidone-6-carboxylic acid (Acp)

✍ Scribed by D.S. Kemp; Paul McNamara


Book ID
104221142
Publisher
Elsevier Science
Year
1982
Tongue
French
Weight
217 KB
Volume
23
Category
Article
ISSN
0040-4039

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Amino acids derivatives that stabilize s
✍ D.S. Kemp; Eric T. Sun 📂 Article 📅 1982 🏛 Elsevier Science 🌐 French ⚖ 109 KB

A six-step synthesis is reported of LL-3-amino-2-piperidone-6-carboxylic acid from C-homoserine lactone and the mono-t-butyl ester of fj-benzyloxycarbonylaminomalonic acid. Evidence of chiral integrityziscussed.