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Amino acid substitutions in two functional mutants of yeast alcohol dehydrogenase

✍ Scribed by WILLS, CHRISTOPHER; JÖRNVALL, HANS


Book ID
109714343
Publisher
Nature Publishing Group
Year
1979
Tongue
English
Weight
589 KB
Volume
279
Category
Article
ISSN
0028-0836

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Functional mutants of yeast alcohol dehy
✍ Christopher Wills; Julia Phelps 📂 Article 📅 1978 🏛 Springer 🌐 English ⚖ 921 KB

Repeated selection of petite (respiratorily incompetent) Saccharomyces cerevisiae on medium containing allyl alcohol, both on plates and in the turbidostat, results in mutants with a remarkably similar response. Most of the mutations affect the constitutive alcohol dehydrogenase, resulting in enzyme