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Amino acid substitutions in the nonstructural region 5A of hepatitis C virus genotypes 2a and 2b and its relation to viral load and response to interferon

✍ Scribed by Makoto Kobayashi; Kazumasa Watanabe; Masatoshi Ishigami; Kenichi Murase; Hiroshi Ito; Koji Ukai; Motoyoshi Yano; Kenji Takagi; Masaki Hattori; Shinichi Kakumu; Kentaro Yoshioka


Book ID
119392251
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
254 KB
Volume
97
Category
Article
ISSN
0002-9270

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of patients with a high likelihood of response to IFN-b. In chronic hepatitis C virus (HCV) infection, geno-(HEPATOLOGY 1997;25:750-753.) types other than genotype 1b of HCV (HCV-1b) and low serum HCV-RNA levels are known to be associated with favorable outcome of interferon alfa (IFN-a) therapy. In