Amino-acid sequence study in peptides by mass spectometry-II. Investigation of pentadeuterobenzoyl-peptide methyl esters
β Scribed by J. P. Kamerling; W. Heerma; Th. J. Penders; J. F. G. Vliegenthart
- Publisher
- John Wiley and Sons
- Year
- 1968
- Tongue
- English
- Weight
- 284 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1076-5174
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β¦ Synopsis
The utility of benzoyl and pentadeuterobenzoyl derivatives of peptide methyl esters for mass spectrometric analysis was investigated. The mass spectra of the glu-his and the Val-tyr-pro derivatives are discussed. Treatment of the peptide methyl esters with the mixed benzoic-ethylcarbonic anhydride did in some cases lead to benzoyl derivatives as well as to ethoxycarbonyl derivatives. * For Part I see Ref. 3.
π SIMILAR VOLUMES
S)-ctMethyimethionine, (S)-ctMethylleucine, 2-aminoisobutyric acid and (S)-otMethylphenylalanine have been incorporated by solid phase peptide strategy in a peptide sequence. The coupling reactions of these Boc-ctMe amino acids and of the following residue in the sequence were readily achieved afte
The thermally induced formation of methyl-and phenylthiohydantoin amino acid derivatives from the corresponding N-methyl-and N-phenylthiourea derivatives of amino acids and peptides has been shown to occur in the mass spectrometer. A comparison of the mass spectra of a number of amino acid thiourea