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Amino acid metabolism and cell volume regulation in the little skate,Raja erinacea. I. Oxidation

✍ Scribed by King, Patricia A. ;Cha, Chung-Ja ;Goldstein, Leon


Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
745 KB
Volume
212
Category
Article
ISSN
0022-104X

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✦ Synopsis


Abstract

The capacity of isolated tissues of the little skate (Raja erinacea) to oxidize β‐alanine, sarcosine, and taurine, and the role of amino acid oxidation in the modulation of intracellular free amino acid concentrations was investigated in vitro. Liver was found to be the primary site of β‐alanine and sarcosine oxidation. Chronic acclimation of skates to half‐strength sea water increased in vitro oxidation of β‐alanine and alanine by liver slices. Taurine oxidation could not be detected in any of the tissues tested. In vivo studies showed that taurine is excreted intact and that excretion increases significantly following acute acclimation of skates to half‐strength sea water.


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