𝔖 Bobbio Scriptorium
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Amine precursor therapy: Manipulation of brain amine activity with precursor amino acid

✍ Scribed by TERUO NAKAJIMA


Book ID
108961554
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
723 KB
Volume
51
Category
Article
ISSN
1323-1316

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Optically active pheniramine by enantios
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Pheniramine (3a) was prepared throt gh enantioselective hydrogenation of various precursor compounds catalyzed by Ru(II)/BINAP complexes. In the case of N,N-dialkyl-3-phenyl-3-(2-pyridyl)allylamines (1 and 2) only the (Z)-isomer shows a satisfactory reactivity; moreover the chemoselectivity is affec