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Amiloride protects against pentylenetetrazole-induced kindling in mice

✍ Scribed by Atif Ali; Farhan Jalees Ahmad; Krishna Kolappa Pillai; Divya Vohora


Book ID
110008797
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
130 KB
Volume
145
Category
Article
ISSN
0007-1188

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Repeated administration of pentylenetetrazol (PTZ, 30 mglkg, thrice a week for 9 weeks) produced chemical kindling when mice were challenged with a subconvulsive dose of the convulsant. These animals were also found to be susceptible to seizures after a subconvulsant dose of a beta-carboline, (FG 71