## Abstract __N__,__N__′‐Alkylidenebisamides 1, totally unsuitable as amidoalkylating agents toward phosphorous acid, react with its “activated” form prepared “in situ” from phosphorus(III) chloride and acetic acid to give the desired 1‐aminoalkylphosphonic acids 2 in high yields.
✦ LIBER ✦
Amidoalkylation of phosphorous acid
✍ Scribed by Józef Oleksyszyn; Ewa Gruszecka
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- French
- Weight
- 164 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Amidoalkylation of phospbarous acid by the reaction of mixture of phosphorous acid and amide with carbonyl compounds in acetic anbdri. de, followed by hydrolysis to give l-aminoalkanephosphonic acids, is described.
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