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Amide Formation in One Pot from Carboxylic Acids and Amines via Carboxyl and Sulfinyl Mixed Anhydrides

✍ Scribed by Zambroń, Bartosz K.; Dubbaka, Srinivas R.; Marković, Dean; Moreno-Clavijo, Elena; Vogel, Pierre


Book ID
120277885
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
349 KB
Volume
15
Category
Article
ISSN
1523-7060

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One-Pot synthesis of (2E)- and (2E, 4E)-
✍ Wen-Juan Xiao; Li-Lan Shi; Zheng-Qing Chen; Yao-Zeng Huang; S. A. Lang 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 395 KB

Di-n-butyl telluride, 2-bromoacetylisobutylamide (or 2-bromoacetylpiperidide) react directly with saturated or +unsaturated aldehydes at room temperature in the presence of potassium carbonate(s) to afford (2E)-, or (2E, 4E)-unsaturated carboxylic acid amides, respectively, in excellent yields with