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Amelioration of hepatic ischemia/reperfusion injury with intercellular adhesion molecule-1 antisense oligodeoxynucleotides

✍ Scribed by R Ghobrial; F Amersi; K Stecker; H Kato; J Melinek; J Singer; A Mhoyan; R.W Busuttil; J.W Kupiec–Weglinski; S.M Stepkowski

Book ID
117230184
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
60 KB
Volume
33
Category
Article
ISSN
0041-1345

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Intercellular adhesion molecule-1 (ICAM-1) is important in neutrophil-dependent injury. We investigated the effects of monocyte chemoattractant protein-1 (MCP-1) produced by Kupffer cells on ICAM-1 expression after ischemia-reperfusion in rat liver by occluding the portal vein for 30 minutes. Serum