✦ LIBER ✦

Alzheimer's disease: Transgenic models to test new chemicals and pharmaceuticals

✍ Scribed by Christopher C.J. Miller; Brian H. Anderton

Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 455 KB
Volume: 3
Category: Article
ISSN: 0958-1669
DOI: 10.1016/0958-1669(92)90016-c

No coin nor oath required. For personal study only.

✦ Synopsis

Alzheimer's disease is the most common form of senile dementia and is predicted to become even more prevalent as the proportion of elderly in the population increases over the next few decades. As yet, there are no effective treatments for the disorder. A major limitation to identifying new drugs and therapeutic targets for Alzheimer's disease has been the absence of an animal model displaying typical Alzheimer's pathology. Transgenic technology is now providing a powerful new approach for the development of animal models of Alzheimer's disease.

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