Susceptibility genes for familial Alzhei
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Dr. Lindsay A. Farrer; Ligaya Stice
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Article
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1993
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John Wiley and Sons
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English
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Linkage data from 92 FAD kindreds were analyzed by lod score analysis under various assumptions of disease penetrance, marker allele frequencies, and heterogeneity. Multilocus linkage analysis supports the existence of a gene in 40%-65% of families with predominantly late-onset illness (after age 65