Cdk5, a therapeutic target for Alzheimer
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Li-Huei Tsai; Ming-Sum Lee; Jonathan Cruz
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Article
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2004
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Elsevier Science
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English
β 124 KB
Alzheimer's disease (AD) represents the leading cause for senile dementia affecting more than 4 million people worldwide. AD patients display a triad of pathological features including brain atrophy caused by neuronal loss, h-amyloid plaque and neurofibrillary tangles. We previously show that Cyclin