A representative region of the nucleus basalis of Meynert was investigated in 11 patients with idiopathic Parkinson's disease and compared with the identical region in 13 age-matched control subjects. Simultaneously, the cerebral cortex and the nucleus basalis i n the patients with Parkinson's disea
Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis
β Scribed by Dr. Peter J. Whitehouse; Donald L. Price; Arthur W. Clark; Joseph T. Coyle; Mahlon R. DeLong
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 691 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0364-5134
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Recent studies indicate that there is a marked reduction in trkA-containing nucleus basalis neurons in end-stage Alzheimer's disease (AD). We used unbiased stereological counting procedures to determine whether these changes extend to individuals with mild cognitive impairment (MCI) without dementia
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