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Alzheimer cytoskeletal pathology: From microtubule associated protein tau to paired helical filaments


Book ID
123332789
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
156 KB
Volume
11
Category
Article
ISSN
0197-4580

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Alzheimer's disease is characterized by the progressive deposition of two types of fibers in the affected brains, the amyloid fibers (consisting of the Abeta peptide, generating the amyloid plaques) and paired helical filaments (PHFs, made up of tau protein, forming the neurofibrillary tangles). Whi