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Alternative Translations of a Single RNA Message: An Identity Switch of (2S,3R)-4,4,4-Trifluorovaline between Valine and Isoleucine Codons

โœ Scribed by Pin Wang; Alfio Fichera; Krishna Kumar; David A. Tirrell

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
151 KB
Volume
116
Category
Article
ISSN
0044-8249

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Alternative Translations of a Single RNA
Alternative Translations of a Single RNA Message: An Identity Switch of (2S,3R)-4,4,4-Trifluorovaline between Valine and Isoleucine Codons
โœ Pin Wang; Alfio Fichera; Krishna Kumar; David A. Tirrell ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 151 KB

The sequence of a protein is, under normal circumstances, determined uniquely by the sequence of its mRNA. In the following Communication, Kumar, Tirrell, and their co-workers show that this need not be true: 4,4,4-trifluorovaline can be assigned either to valine codons or to isoleucine codons, depe