Alternative nucleotide incision repair pathway for oxidative DNA damage
β Scribed by Ischenko, Alexander A.; Saparbaev, Murat K.
- Book ID
- 109802727
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 191 KB
- Volume
- 415
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/415183a
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## Abstract Oxidative damage represents the most significant insult to organisms because of continuous production of the reactive oxygen species (ROS) in vivo. Oxidative damage in DNA, a critical target of ROS, is repaired primarily via the base excision repair (BER) pathway which appears to be the