In 6 different Burkitt lymphoma cell lines with t(2;8) variant translocations (JI, LY66, LY91, B U I , BL64, JBU) the breakpoints on chromosome 8q+ were mapped in relation to each other and to c-myc by in situ hybridization. The probes used were derived from chromosome 8q24 and comprised a c-myc pro
β¦ LIBER β¦
Alternative involvement of two cytogenetically distinguishable breakpoints on chromosome 8 in Burkitt's lymphoma associated translocations
β Scribed by George Manolov; Yanka Manolova; George Klein; Gilbert Lenoir; Albert Levan
- Book ID
- 119103235
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 254 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0165-4608
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## Abstract We have analyzed the type of __MYC/IG__ heavyβchain locus (__IGH__) rearrangement present in 15 patients affected by t(8; 14)βpositive primary Burkitt's lymphoma or acute lymphoblastic leukemia of the L3 type in an attempt to map in detail the locations of the chromosome 8 and chromosom