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Altered regulation of the recA gene in Escherichia coli strains carrying a recA-linked suppressor of lexA

✍ Scribed by Thomas, A. ;Lloyd, R. G.

Publisher: Springer
Year: 1980
Tongue: English
Weight: 297 KB
Volume: 179
Category: Article
ISSN: 0026-8925
DOI: 10.1007/bf00425464

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✦ Synopsis

A mutant strain of E. coli displaying altered regulation of the recA gene was isolated as a revertant of a lexA3 recA200 double mutant which showed improved DNA repair and recombination functions. The mutation (alc-24) was located between srl and recA200 and caused synthesis of high levels of recA protein in both lexA + and lexA3 strains. The possibility that alc-24 defines the regulatory site for recA is discussed.

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