𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Altered RB expression is a prognostic clinical marker involved in human bladder tumorigensis

✍ Scribed by Willian F. Benedict

Book ID
102304458
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
310 KB
Volume
50
Category
Article
ISSN
0730-2312

No coin nor oath required. For personal study only.

✦ Synopsis

We are now beginning to understand the development of bladder cancer at the molecular level. Tumor evolution involves the interaction of both oncogenes and tumor suppressor genes. One of the key tumor suppressor genes in this process is the retinoblastoma (RB) gene. Much has been learned recently about the role of this gene in the tumor progression and prognosis of bladder cancer, although several questions are still unanswered. The progress made on this subject in our laboratory as well as others will be the focus of this report.

πŸ“œ SIMILAR VOLUMES

Protein expression and amplification of
Protein expression and amplification of AIB1 in human urothelial carcinoma of the bladder and overexpression of AIB1 is a new independent prognostic marker of patient survival
✍ Jun-Hang Luo; Dan Xie; Meng-Zhong Liu; Wei Chen; Yong-Dong Liu; Guo-Qing Wu; Hsi πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 French βš– 342 KB πŸ‘ 1 views

## Abstract __AIB1__, a candidate oncogene in human breast cancer, is frequently amplified and overexpressed in several types of human cancers, but the status of __AIB1__ amplification and expression in urothelial carcinoma of the bladder (UC) and its clinical/prognostic significance is unclear. In