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Altered phenotype of HT29 colonic adenocarcinoma cells following expression of the DCC gene

โœ Scribed by Velcich, Anna; Corner, Georgia; Palumbo, Lisa; Augenlicht, Leonard


Book ID
110062046
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
365 KB
Volume
18
Category
Article
ISSN
0950-9232

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Sulindac sulfide (SS), the active metabolite of the colon cancer chemopreventive compound sulindac, inhibits the proliferation of HT-29 colon cancer cells mainly by inducing cell quiescence. We determined by bivariate flow-cytometric analysis both the DNA and cyclin protein content of individual cel