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Altered Mitochondrial Gene Expression in Human Gestational Trophoblastic Diseases

โœ Scribed by S Durand; C Dumur; A Flury; P Abadie; L Patrito; O Podhajcer; S Genti-Raimondi


Book ID
114477892
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
339 KB
Volume
22
Category
Article
ISSN
0143-4004

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Mitochondrial DNA (mtDNA) mutations have been implicated in a wide range of human disease. However, its role in gestational trophoblastic disease remains unclear. In this study, the entire mitochondrial genome of 10 hydatidiform moles (HM) and one choriocarcinoma were examined by automated DNA seque