Altered imprinting, promoter usage, and expression of insulin-like growth factor-II gene in gestational trophoblastic diseases
β Scribed by Sung J.o Kim; Sang Eun Park; Chan Lee; Sun Young Lee; I.n H.o Kim; Hee Jung An; Y.u-Kyoung Oh
- Book ID
- 114101344
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 281 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0090-8258
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Insulin-like growth factor II (IGF-II) plays significant roles in the growth and development of mammals through the regulation of mitogenesis and cell survival. Previously, IGF-II mRNA transcripts within the CNS were detected in the choroid plexus and leptomeninges (DeChiara et al., 1991). The objec
## Abstract This study examined the frequency of loss of imprinting (LOI) and expression of the insulinβlike growth factor 2 (__IGF2__) gene, and their relationship to selected clinical and pathological factors, in a well defined series of 90 Chinese patients with gastric cancer (GC) and 90 matched