Altered expression of HLA class I antige
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Ingibjörg Guđmundsdóttir; Jón Gunnlaugur Jónasson; Helgi Sigurđsson; Kristrún Ól
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Article
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2000
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John Wiley and Sons
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French
⚖ 620 KB
Loss of surface expression of class I major histocompatibility antigens is commonly observed in malignant tumors and has been considered one of the mechanisms for escape from cytotoxic T cells. However, natural killer cells kill cells lacking HLA class I antigens. In the present study, we characteri