Altered expression of glutamate transporters in experimental autoimmune encephalomyelitis
β Scribed by Makoto Ohgoh; Takahisa Hanada; Terence Smith; Toshihide Hashimoto; Masataka Ueno; Yoshiharu Yamanishi; Masahiko Watanabe; Yukio Nishizawa
- Book ID
- 114137584
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 337 KB
- Volume
- 125
- Category
- Article
- ISSN
- 0165-5728
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## Abstract Regulation of extracellular excitotoxins by glial and neuronal glutamate transporters is critical to maintain synaptic terminal integrity. Factors interfering with the normal functioning of these transporters might be involved in neurodegeneration. Among them, recent studies have shown
We previously reported that recovery of Lewis rats from experimental autoimmune encephalomyelitis (EAE) is associated with the appearance of suppressor T cells (Ts). These Ts secrete TGF-beta which down-regulates the production of inflammatory cytokines by the effector T cells that mediate this dise