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Altered expression of exon 6 deleted progesterone receptor variant mRNA between normal human breast and breast tumour tissues

✍ Scribed by Leygue, E; Dotzlaw, H; Watson, P H; Murphy, L C


Book ID
110002183
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
112 KB
Volume
80
Category
Article
ISSN
0007-0920

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## Abstract The human progesterone receptor (PR) is a ligand‐activated nuclear transcription factor that mediates progesterone action in target tissues. We found a novel alternatively spliced variant (ASV) of the PR mRNA in breast cancer tissues. The deleted transcript was characterized by an out‐o