Altered distribution of debrisoquine oxidation phenotypes in patients with systemic lupus erythematosus
β Scribed by Alan N. Baer; C. B. McAllister; Grant R. Wilkinson; Raymond L. Woosley; Theodore Pincus
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 766 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0004-3591
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## Objective: Systemic lupus erythematosus (sle) is a systemic autoimmune disease characterized by b cell hyperactivity and defective t cell functions, including interleukin-2 production and proliferation. the defects in t cell function may result from underlying defects in antigen-presenting cell
Sera obtained from fifty-five patients with active systemic lupus erythematosus (SLE) and from four patients with mixed connective tissue disease (MCTD) previously shown by immunofluorescence and by double immunodiffusion to possess antinuclear antibodies, were tested for the presence of natural ant