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Altered B cell receptor signaling in human systemic lupus erythematosus

✍ Scribed by Scott A. Jenks; Iñaki Sanz

Book ID
113482089
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
305 KB
Volume
8
Category
Article
ISSN
1568-9972

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## Abstract ## Objective B lymphocyte depletion has recently emerged as a promising approach to the treatment of systemic lupus erythematosus (SLE). As part of a phase I/II dose‐ranging trial of rituximab in the treatment of SLE, we evaluated the fate of discrete B cell subsets in the setting of s