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Alterations to the Primer Grip of p66 HIV-1 Reverse Transcriptase and Their Consequences for Template-Primer Utilization †

✍ Scribed by Ghosh, Madhumita; Jacques, Pamela S.; Rodgers, David W.; Ottman, Michele; Darlix, Jean-Luc; Le Grice, Stuart F. J.


Book ID
126286630
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
688 KB
Volume
35
Category
Article
ISSN
0006-2960

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## Abstract The p66/p51 human immunodeficiency virus type 1 reverse transcriptase is a heterodimer with identical N‐terminal amino acid sequences. The enzyme contains two polymerization domains and one RNase H domain, which is located at the C‐terminus of the p66 subunit. Both polymerization domain