✦ LIBER ✦

Specific Targeting of Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. 2. Stereoselective Interaction to Overcome the Effects of Drug Resistant Mutations

✍ Scribed by Butini, Stefania; Brindisi, Margherita; Cosconati, Sandro; Marinelli, Luciana; Borrelli, Giuseppe; Coccone, Salvatore Sanna; Ramunno, Anna; Campiani, Giuseppe; Novellino, Ettore; Zanoli, Samantha; Samuele, Alberta; Giorgi, Gianluca; Bergamini, Alberto; Mattia, Michela Di; Lalli, Silvana; Galletti, Bruno; Gemma, Sandra; Maga, Giovanni

Book ID: 120318950
Publisher: American Chemical Society
Year: 2009
Tongue: English
Weight: 728 KB
Volume: 52
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm801395v

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Specific Targeting Highly Conserved Resi

Specific Targeting Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. Design, Synthesis, and Biological Evaluation of Novel, Potent, and Broad Spectrum NNRTIs with Antiviral Activity

✍ Fattorusso, Caterina; Gemma, Sandra; Butini, Stefania; Huleatt, Paul; Catalanott 📂 Article 📅 2005 🏛 American Chemical Society 🌐 English ⚖ 505 KB

Selective targeting of the HIV-1 reverse

Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the “primer grip” region by pyrrolobenzoxazepinone non-nucleoside inhibitors correlates with increased activity towards drug-resistant mutants

✍ Samantha Zanoli; Sandra Gemma; Stefania Butini; Margherita Brindisi; Bhupendra P 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 636 KB

50 Biochemical analysis of human immunod

50 Biochemical analysis of human immunodeficiency virus type-1 reverse transcriptase with mutations at methione 184 in the highly conserved YMDD region: Mechanism for 1-β-L nucleoside drug resistance: JE Wilson, JL Martin, A Aulabaugh, LL Wright, S McPherson2, JK Wakefield2, S Jablonski2, CD Morrow2, and PA Furman. Division of Virology, Burroughs Wellcome Co., Research Triangle Park, NC, USA, and 2Department of Microbiology, University of Alabama at Birmingham, Birmingham, Al, USA

📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 84 KB