Alterations of the Transforming Growth Factor-(β Signaling Pathway in Hepatocellular Carcinomas Induced Endogenously and Exogenously in Rats
✍ Scribed by Sasaki, Yasutaka ;Tsujiuchi, Toshifumi ;Murata, Nao ;Tsutsumi, Masahiro ;Konishi, Yoichi
- Book ID
- 108581968
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2001
- Tongue
- English
- Weight
- 180 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0910-5050
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## Background: Resistance to the potent growth inhibitory effects of transforming growth factor-beta (tgf-beta) is a characteristic of many malignancies. tgf-beta insensitivity has been attributed to alterations in the number and function of the tgf-beta receptors as well as disturbances of downstr